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Article

Therapeutic strategies of metabolic reprogramming in non-small cell lung carcinoma.

Annals of medicine - 1 Dec 2026

Liu Jiajun, Qian Fenhong

Abstract excerpt

BACKGROUND: Non-small cell lung carcinoma (NSCLC) remains a leading cause of cancer-related mortality worldwide, with existing therapies frequently hindered by drug resistance and immunosuppression. Metabolic reprogramming (glycolysis, lipid metabolism, and amino acid metabolism) has emerged as a core hallmark driving NSCLC progression, tumor microenvironment (TME) remodeling, and treatment failure, transcending...

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Share to Antineoplastic Agents
Share to Carcinoma, Non-Small-Cell Lung
Share to Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycolysis

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Source

Identifiers

PMID: 41987491
DOI: 10.1080/07853890.2026.2652110

Genes

ALK
CPT1A
DPP4
EGFR
GFPT2
GLUD1
KRAS
PFKFB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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