Article
Revisiting the biological role of the Warburg effect: Evolving perspectives on cancer metabolism
28 Jul 2025
Abstract excerpt
Cancer cells exhibit metabolic reprogramming towards a glycolysis-dominant profile. This shift, known as the Warburg effect, enhances cancer cell survival, growth, and metastasis by increasing glucose uptake and lactate production. It also meets the high anabolic demands of proliferation by providing important biosynthetic precursors. Despite its long-standing discovery, the origins and roles of the Warburg...
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