Article

Fragile X Messenger Ribonucleoprotein 1 (FMR1), a novel inhibitor of osteoblast/osteocyte differentiation, regulates bone formation, mass, and strength in young and aged male and female mice.

2022-12-15

Abstract excerpt

<title>Abstract</title> <p>Fragile X Messenger Ribonucleoprotein 1 (FMR1) gene premutations lead to fragile X syndrome, cognitive disorders, and, in some individuals, scoliosis and craniofacial abnormalities. Four-month-old male <italic>FMR1</italic>-deficient mice exhibit a mild increase in cortical and cancellous femoral bone mass. However, consequences of FMR1-deficiency in bone of young and aged and of male a...

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Literature Corpus work: e4820523-6462-5937-9a4d-998c03fb49a3
DOI: 10.21203/rs.3.rs-2338908/v1

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