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Article

A novel role for interferon regulatory factor 1 (IRF1) in regulation of bone metabolism.

Journal of cellular and molecular medicine - 1 Aug 2014

Salem Sandra, Gao Chan, Li Ailian, Wang Huifen, Nguyen-Yamamoto Loan, Goltzman David, Henderson Janet E, Gros Philippe

Abstract excerpt

Increased risk of bone fractures is observed in patients with chronic inflammatory conditions, such as inflammatory bowel disease and rheumatoid arthritis. Members of the Interferon Response Factor family of transcriptional regulators, IRF1 and IRF8, have been identified as genetic risk factors for several chronic inflammatory and autoimmune diseases. We have investigated a potential role for the Irf1 gene in...

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Identifiers

PMID: 24954358
DOI: 10.1111/jcmm.12327
PMCID: PMC4152406

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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