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Article

Epigenetic Regulation of Skeletal Tissue Integrity and Osteoporosis Development.

International journal of molecular sciences - 12 Jul 2020

Chen Yu-Shan, Lian Wei-Shiung, Kuo Chung-Wen, Ke Huei-Jing, Wang Shao-Yu, Kuo Pei-Chen, Jahr Holger, Wang Feng-Sheng

Abstract excerpt

Bone turnover is sophisticatedly balanced by a dynamic coupling of bone formation and resorption at various rates. The orchestration of this continuous remodeling of the skeleton further affects other skeletal tissues through organ crosstalk. Chronic excessive bone resorption compromises bone mass and its porous microstructure as well as proper biomechanics. This accelerates the development of osteoporotic...

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Identifiers

PMID: 32664681
DOI: 10.3390/ijms21144923
PMCID: PMC7404082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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