Article

A marker-free co-selection strategy for high efficiency human genome engineering

2017-03-15

Abstract excerpt

<h4>ABSTRACT</h4> Targeted genome editing using engineered nucleases facilitates the creation of bona fide cellular models for biological research and may be applied to human cell-based therapies. Broadly applicable and versatile methods for increasing the levels of gene editing in cell populations remain highly desirable due to the variable efficiency between distinct genomic loci and cell types. Harnessing the...

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Literature Corpus work: e43f9d0d-dafe-5247-9864-4f109cb86d85
DOI: 10.1101/116251

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