LZTS2 Emerges as a Regulator of Craniofacial Development and Modulator of DYRK1A

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Precise control of DYRK1A dosage is essential for embryonic development, including craniofacial morphogenesis. While LZTS2 is among the most consistently identified DYRK1A-interacting proteins, its roles in embryonic development remain incompletely understood, and its potential contribution to craniofacial development has not been examined. Xenopus laevis was used to test t...

Topics

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• Craniofacial Abnormalities
• Gene Knockdown Techniques
• Head
• MAP Kinase Signaling System
• Odontogenesis
• Ribosomal Protein S6 Kinases, 90-kDa
• RNA, Small Interfering
• Tooth

Identifiers and source

Literature Corpus work

e432716f-d3c8-53bf-ac0a-a9a937211305

DOI

10.64898/2026.03.31.715576