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Article

MNB/DYRK1A as a multiple regulator of neuronal development

11 Nov 2010

Abstract excerpt

MNB/DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that has been strongly conserved across evolution. There are substantial data implicating MNB/DYRK1A in brain development and adult brain function, as well as in neurodegeneration and Down syndrome pathologies. Here we review our current understanding of the neurodevelopmental activity of MNB/DYRK1A. We discuss...

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PMID: 21156027
DOI: 10.1111/j.1742-4658.2010.07954.x

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