Article

<i>SMARCA4</i> Mutations in <i>KRAS</i>-mutant Lung Adenocarcinoma: A Multi-cohort Analysis

2020-06-29

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> KRAS is a key oncogenic driver in lung adenocarcinoma (LUAD). Chromatin-remodeling gene SMARCA4 was co-mutated with KRAS in LUAD; however, the impact of SMARCA4 mutations on clinical outcome has not been adequately established. This study sought to shed light on the clinical significance of SMARCA4 mutations in LUAD. <h4>Methods</h4> The association of SMARCA4 mutations with s...

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Literature Corpus work: e4237d94-8b61-577e-90fb-409c62f2c403
DOI: 10.1101/2020.06.27.20135020

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