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Article

Clinicopathological characteristics and treatment outcomes of advanced SMARCA4-deficient thoracic tumors.

Cancer medicine - 1 Jan 2024

Wang Anni, Jin Yueping, Cao Zhengqi, Lu Li, Li Ziming

Abstract excerpt

PURPOSE: SMARCA4-deficient thoracic tumors, characterized by distinct clinicopathological, morphological, immunohistochemical, and genetic features, differ significantly from conventional non-small-cell lung carcinomas (NSCLCs). This group encompasses both SMARCA4-deficient NSCLCs (SMARCA4-NSCLCs) and SMARCA4-deficient undifferentiated tumors (SMARCA4-UTs). The efficacy of PD-1 inhibitors in treating...

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Identifiers

PMID: 38124509
DOI: 10.1002/cam4.6809
PMCID: PMC10807565

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