The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer.

doi:10.1158/1078-0432.CCR-20-1825

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Article

The Genomic Landscape of SMARCA4 Alterations and Associations with Outcomes in Patients with Lung Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2020

Schoenfeld Adam J, Bandlamudi Chai, Lavery Jessica A, Montecalvo Joseph, Namakydoust Azadeh, Rizvi Hira, Egger Jacklynn, Concepcion Carla P, Paul Sonal, Arcila Maria E, Daneshbod Yahya, Chang Jason, Sauter Jennifer L, Beras Amanda, Ladanyi Marc, Jacks Tyler, Rudin Charles M, Taylor Barry S, Donoghue Mark T A, Heller Glenn, Hellmann Matthew D, Rekhtman Natasha, Riely Gregory J

Abstract excerpt

PURPOSE: SMARCA4 mutations are among the most common recurrent alterations in non-small cell lung cancer (NSCLC), but the relationship to other genomic abnormalities and clinical impact has not been established. EXPERIMENTAL DESIGN: To characterize SMARCA4 alterations in NSCLC, we analyzed the genomic, protein expression, and clinical outcome data of patients with SMARCA4 alterations treated at Memorial Sloan...

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PMID: 32709715
DOI: 10.1158/1078-0432.CCR-20-1825
PMCID: PMC7641983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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