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Article

Clinicopathological characteristics and therapeutic outcomes in patients with non-small cell lung cancer harboring SMARCA4 mutations.

Annals of medicine - 1 Dec 2026

Liu Yan, Li Hui, Li Xiang, Cui Heran, Li Rixin, Zhu Jing, Cui Hongxia, Liu Ying, Cheng Ying

Abstract excerpt

OBJECTIVE: To investigate the clinical characteristics and impact of SMARCA4 mutations in patients with non-small cell lung cancer (NSCLC). METHODS: A total of 2,821 patients with NSCLC who underwent next-generation sequencing were retrospectively included. The frequency and types of SMARCA4 mutations and co-mutations were determined, and the clinical outcomes were assessed. RESULTS: SMARCA4 mutations were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41593906
DOI: 10.1080/07853890.2026.2620201
PMCID: PMC12854217

Genes

SMARCA4
EGFR
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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