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Impact of IRS-1 rs956115 and CYP2C19 rs4244285 Genotypes on Clinical Outcome of Patients Undergoing PCI

2021-11-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background </bold>insulin receptor substrate-1 (IRS-1) rs956115 is associated with vascular risk in patients with coronary artery disease (CAD) and concomitant diabetes. CYP2C19 rs4244285 modulates clopidogrel responsiveness and predicts outcome of CAD. We designed this study to explore the association between IRS-1 rs956115, CYP2C19 rs4244285, and platelet reactivity as well as 1...

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Literature Corpus work
e40f7bdb-3921-58ac-b72c-3a09b545f14a
DOI
10.21203/rs.3.rs-1100332/v1
Open publication

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