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Article

CRISPLD1 rs12115090 polymorphisms alters antiplatelet potency of clopidogrel in coronary artery disease patients in Chinese Han.

Gene - 15 Dec 2018

Wang Jie-Ya, Zhang Yan-Jiao, Li He, Hu Xiao-Lei, Li Mu-Peng, Song Pei-Yuan, Ma Qi-Lin, Peng Li-Ming, Chen Xiao-Ping

Abstract excerpt

BACKGROUND: Dual antiplatelet therapy (DAPT) with aspirin and clopidogrel is a recommended treatment for coronary artery disease (CAD) patients undergoing percutaneous coronary intervention (PCI) to reduce the rate of ischemic events and stent thrombosis. However, high on-treatment platelet reactivity (HTPR) during clopidogrel therapy for some patients may lead to outcome failure and occurrence of cardiovascular...

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Source

Identifiers

PMID: 30096456
DOI: 10.1016/j.gene.2018.08.027

Genes

CAD
CRISPLD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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