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Article

Effect of cytochrome p450 polymorphisms on platelet reactivity after treatment with clopidogrel in acute coronary syndrome.

The American journal of cardiology - 15 Apr 2008

Frere Corinne, Cuisset Thomas, Morange Pierre-Emmanuel, Quilici Jacques, Camoin-Jau Laurence, Saut Noémie, Faille Dorothee, Lambert Marc, Juhan-Vague Irène, Bonnet Jean-Louis, Alessi Marie-Christine

Abstract excerpt

Genetic polymorphisms of cytochrome P450 (CYP) isoforms may promote variability in platelet response to clopidogrel. This study was conducted to analyze, in 603 patients with non-ST elevation acute coronary syndromes, the effect of CYP3A4, CYP3A5, and CYP2C19 gene polymorphisms on clopidogrel response and post-treatment platelet reactivity assessed by adenosine diphosphate (ADP)-induced platelet aggregation,...

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Source

Identifiers

PMID: 18394438
DOI: 10.1016/j.amjcard.2007.11.065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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