Association of PEAR1 genetic variants with platelet reactivity in response to dual antiplatelet therapy with aspirin and clopidogrel in the Chinese patient population after percutaneous coronary intervention.

doi:10.1016/j.thromres.2016.02.031

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Article

Association of PEAR1 genetic variants with platelet reactivity in response to dual antiplatelet therapy with aspirin and clopidogrel in the Chinese patient population after percutaneous coronary intervention.

Thrombosis research - 1 May 2016

Yao Yi, Tang Xiao-Fang, Zhang Jia-Hui, He Chen, Ma Yuan-Liang, Xu Jing-Jing, Song Ying, Liu Ru, Meng Xian-Min, Song Lei, Chen Jue, Wang Miao, Xu Bo, Gao Run-Lin, Yuan Jin-Qing

Abstract excerpt

INTRODUCTION: Platelet Endothelial Aggregation Receptor-1 (PEAR1) is a recently reported platelet transmembrane protein which plays an important role in platelet aggregation. The aim of this study was to investigate whether PEAR1 genetic variations were associated with platelet reactivity as asse...

Topics

Aged
Asian People
Aspirin
Blood Platelets
China
Clopidogrel
Coronary Disease
Female
Haplotypes
Humans
Male
Middle Aged
Percutaneous Coronary Intervention
Platelet Aggregation

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Platelet Aggregation Inhibitors

Polymorphism, Single Nucleotide

Receptors, Cell Surface

Ticlopidine

Source

Open in PubMed

Identifiers

PMID: 26962983
DOI: 10.1016/j.thromres.2016.02.031

Genes

PEAR1
HPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-26962983-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.