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Article

MirSNPs in clopidogrel metabolism genes predict cardiovascular disease risk: a case-control study and meta-analysis.

Pharmacogenomics - 1 Jan 2021

Sharma Anu Radha, Patagi Sourav, Uk Abdul Razak, Shetty Ranjan, Umakanth Shashikiran, Satyamoorthy Kapaettu, Rai Padmalatha S

Abstract excerpt

Aim: The present study was conducted to decipher the inter-relationship of SNPs and miRNAs involved in pharmacogenomics of clopidogrel on predisposition to cardiovascular diseases (CVDs). Materials & methods: A case-control study was conducted on 410 cases and 386 controls to analyze the association of 13 mirSNPs on CVDs risk. Genotyping was performed by tetra-primer amplification refractory mutation system PCR...

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PMID: 33356544
DOI: 10.2217/pgs-2020-0110

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