Article

58 risk and 34 protective effects of <i>GLP1R</i> on disease phenome and adverse neonatal health

2026-01-26

Abstract excerpt

Cardiometabolic gene-target drugs such as Glucagon-Like Peptide 1 Receptor agonists are used extensively, yet risks and repurposing have not been systematically evaluated across a comprehensive set of diseases. We use Phenome-wide Mendelian Randomization to test GLP1R gene expression and Cholesteryl Ester Transfer Protein (CETP) concentration, two promising cardiometabolic drug targets, on risk of 396 diseases ba...

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Literature Corpus work: e3f9a6ab-eecf-5590-ad64-be1fc8f59025
DOI: 10.64898/2026.01.24.26344404

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