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Article

Mendelian randomization analysis reveals causal effects of blood lipidome on gestational diabetes mellitus.

Cardiovascular diabetology - 11 Sept 2024

Dong Yao, Hu An-Qun, Han Bai-Xue, Cao Meng-Ting, Liu Hai-Yan, Li Zong-Guang, Li Qing, Zheng Ying-Jie

Abstract excerpt

BACKGROUND: Observational studies have revealed associations between maternal lipid metabolites and gestational diabetes mellitus (GDM). However, whether these associations are causal remain uncertain. OBJECTIVE: To evaluate the causal relationship between lipid metabolites and GDM. METHODS: A two-sample Mendelian randomization (MR) analysis was performed based on summary statistics. Sensitivity analyses,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39261922
DOI: 10.1186/s12933-024-02429-2
PMCID: PMC11391602

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