Article

A Trans-Omic Mendelian Randomization Study of Parental Lifespan Uncovers Novel Aging Biology and Drug Candidates for Human Healthspan Extension

2020-07-10

Abstract excerpt

The study of parental lifespan has emerged as an innovative tool to advance aging biology and our understanding of the genetic architecture of human longevity and healthspan. Here, we leveraged summary statistics of a genome-wide association study including over one million parental lifespans to identify genetically regulated genes from the Genotype-Tissue Expression project through a combination of multi-tissue t...

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Literature Corpus work: 6ea8c038-4c9e-5120-a76d-6794028eeb77
DOI: 10.1101/2020.07.06.20147520

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