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Article

Genetic insights into therapeutic targets for gestational diabetes mellitus: a multi-omics analysis.

Naunyn-Schmiedeberg's archives of pharmacology - 1 Apr 2026

Li Qiuya, Zhai Pengyan, Cong Donghang, Zhang Ming, Zhou Wenbo

Abstract excerpt

Gestational diabetes mellitus (GDM) is a prevalent metabolic disorder during pregnancy associated with adverse maternal and fetal outcomes, highlighting the urgent need for novel, genetically supported drug targets due to suboptimal glycemic control and safety concerns with existing therapies. This study integrated cis-expression quantitative trait loci (cis-eQTL) of druggable genes with genome-wide association...

Read the complete abstract on PubMed

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41632246
DOI: 10.1007/s00210-026-05053-x

Genes

GRINA
NRBP1
BTN3A2
GSTM1
LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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