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Article

Implementation of individualised polygenic risk score analysis: a test case of a family of four.

BMC medical genomics - 3 Oct 2022

Corpas Manuel, Megy Karyn, Metastasio Antonio, Lehmann Edmund

Abstract excerpt

BACKGROUND: Polygenic risk scores (PRS) have been widely applied in research studies, showing how population groups can be stratified into risk categories for many common conditions. As healthcare systems consider applying PRS to keep their populations healthy, little work has been carried out demonstrating their implementation at an individual level. CASE PRESENTATION: We performed a systematic curation of PRS...

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Identifiers

PMID: 36192731
DOI: 10.1186/s12920-022-01331-8
PMCID: PMC9531350

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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