Article
PGS Browser: a public platform for personalized polygenic score analysis and interpretation.
Nature communications - 20 Jun 2026
Kolosov Nikita, Reeve Mary P, Briotta Parolo Pietro Della, Kurki Mitja I, Llorens Vincent, Sipila Timo Petteri, Herman Adam, Molotkov Ivan, Aavikko Mervi, Ripatti Samuli, Palotie Aarno, Daly Mark J, Artomov Mykyta
Abstract excerpt
Polygenic scores (PGSs) quantify individual genetic susceptibility to complex diseases and can identify high-risk individuals well before clinical onset. Their clinical translation, however, requires population-based reference resources, standardized benchmarking, and accessible tools for translating individual scores into disease likelihood. In this article, we systematically evaluate 3168 PGS models, primarily...
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