Uncovering CARD14 features in cancer

Abstract excerpt

<title>Abstract</title> <p>Aberrant caspase recruitment domain family member 14 (CARD14) signaling has been strongly associated with inflammatory skin conditions. CARD14 acts as a scaffold protein, ultimately activating the transcription factor NF-KB. Although primarily studied in the context of inflammation, recent research has suggested its potential implications in tumorigenesis. In this study, we gathered TCG...

Topics

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• CARD Signaling Adaptor Proteins
• Cells, Cultured
• Epidermis
• Gene Expression Regulation, Neoplastic
• Guanylate Cyclase
• Neoplasms, Squamous Cell
• NF-kappa B
• Skin Neoplasms

Identifiers and source

Literature Corpus work

e3b6fe66-08e0-5ba2-b8f6-cabc7e3d7a83

DOI

10.21203/rs.3.rs-4305679/v1