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Article

CARD14/CARMA2 Signaling and its Role in Inflammatory Skin Disorders

26 Sept 2018

Abstract excerpt

CARMA proteins represent a family of scaffold molecules which play several crucial biological functions, including regulation of immune response and inflammation, tissue homeostasis, and modulation of G-Protein Coupled Receptor (GPCR) signaling. Among the CARMA proteins, CARD14/CARMA2 and its alternatively spliced isoforms are specifically expressed in epithelial cells and keratinocytes. Recent evidences have...

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PMID: 30319628
DOI: 10.3389/fimmu.2018.02167

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