Article

An exploration of linkage fine-mapping on sequences from case-control studies

2021-12-21

Abstract excerpt

Linkage analysis maps genetic loci for a heritable trait by identifying genomic regions with excess relatedness among individuals with similar trait values. Analysis may be conducted on related individuals from families, or on samples of unrelated individuals from a population. For allelically heterogeneous traits, population-based linkage analysis can be more powerful than genotypic-association analysis. Here, we...

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Literature Corpus work: e39582e2-e930-5d38-b263-f70beea4e45e
DOI: 10.1101/2021.12.18.473306

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