Article
Application of genome-wide SNP data for uncovering pairwise relationships and quantitative trait loci.
Genetica - 1 Jun 2009
Sham P C, Cherny S S, Purcell S
Abstract excerpt
The genetic analysis of quantitative traits in humans is changing as a result of the availability of whole-genome SNP data. Heritability analysis can make use of actual genetic sharing between pairs of individuals estimated from the genotype data, rather than the expected genetic sharing implied by their family relationship. This could provide more accurate heritability estimates and help to overcome the equal...
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