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Article

An exploration of linkage fine-mapping on sequences from case-control studies.

Genetic epidemiology - 1 Feb 2023

Nickchi Payman, Karunarathna Charith, Graham Jinko

Abstract excerpt

Linkage analysis maps genetic loci for a heritable trait by identifying genomic regions with excess relatedness among individuals with similar trait values. Analysis may be conducted on related individuals from families, or on samples of unrelated individuals from a population. For allelically heterogeneous traits, population-based linkage analysis can be more powerful than genotypic-association analysis. Here,...

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Identifiers

PMID: 36047334
DOI: 10.1002/gepi.22502
PMCID: PMC10087369

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