Article

Organisation of gene programs revealed by unsupervised analysis of diverse gene-trait associations

2022-04-08

Abstract excerpt

<h4>ABSTRACT</h4> Genome wide association studies provide statistical measures of gene-trait associations that reveal how genetic variation influences phenotypes. This study develops an unsupervised dimensionality reduction method called UnTANGLeD (Unsupervised Trait Analysis of Networks from Gene Level Data) which organises 16,849 genes into discrete gene programs by measuring the statistical association between...

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Literature Corpus work: e34c1bbb-6345-5e5c-ad71-09c513831abe
DOI: 10.1101/2022.04.07.487559

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