Article

A network-based analysis of the cellular and genetic etiology of disease

2016-01-01

Abstract excerpt

Thousands of disease-associated loci have been identified in genome-wide association studies (GWAS). These loci can span multiple genes and identifying which, if any, of these genes are causal can be challenging. Multiple methods have been developed to identify causal genes, some of which use networks of physical interactions between proteins. The performance of many of these methods may however be limited by thei...

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Literature Corpus work: 84e5bfa8-9a39-5e2f-9d2e-4651257e79c4
DOI: 10.25560/61577

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