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<i>De novo</i> cobalamin biosynthesis, transport and assimilation and cobalamin-mediated regulation of methionine biosynthesis in <i>Mycobacterium smegmatis</i>

2020-11-05

Abstract excerpt

<h4>ABSTRACT</h4> Cobalamin is an essential co-factor in all domains of life, yet its biosynthesis is restricted to some bacteria and archaea. Mycobacterium smegmatis , an environmental saprophyte frequently used as surrogate for the obligate human pathogen, M. tuberculosis , carries approximately 30 genes predicted to be involved in de novo cobalamin biosynthesis. M. smegmatis also encodes multiple cobalamin...

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Literature Corpus work
e2e8d688-c405-5a00-bc36-ab595a75341d
DOI
10.1101/2020.11.04.369181
Open publication

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