Article

Asparagine deprivation causes a reversible inhibition of Human Cytomegalovirus acute virus replication

2019-07-02

Abstract excerpt

As obligate intracellular pathogens, viruses rely on the host cell machinery to replicate efficiently, with the host metabolism extensively manipulated for this purpose. High throughput siRNA screens provide a systematic approach for the identification of novel host-virus interactions. Here, we report a large-scale screen for host factors important for human cytomegalovirus (HCMV), consisting of 6,881 siRNAs. We i...

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Literature Corpus work: e2d95157-2904-5d1e-8321-48d74e942828
DOI: 10.1101/690016

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