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Article

Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic Organoids

2023-04-26

Abstract excerpt

Due to the limitations of available in vitro systems and animal models, we lack a detailed understanding of the pathogenetic mechanisms and have minimal treatment options for liver fibrosis. To overcome this barrier, we engineered a live cell imaging system that identifies collagen producing cells in a human multi-lineage hepatic organoid. This system was adapted for use as a microwell-based platform (i.e., micro...

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Literature Corpus work
e2beb810-4604-5f69-bc1a-d3f6f20b2d92
DOI
10.1101/2023.04.25.538102
Open publication

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Characterization of Pro-Fibrotic Signaling Pathways using Human Hepatic OrganoidsDOI 10.1101/2023.04.25.538102
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