Article

Scalable production of tissue-like vascularised liver organoids from human PSCs

2020-12-02

Abstract excerpt

<h4>ABSTRACT</h4> A lack of physiological parity between 2D cell culture and in vivo , has paved the way towards more organotypic models. Organoids exist for a number of tissues, including the liver. However, current approaches to generate hepatic organoids suffer drawbacks, including a reliance on extracellular matrices (ECM), the requirement to pattern in 2D culture, costly growth factors and a lack of cellula...

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Literature Corpus work: 3ba50f24-2b05-5560-b7fc-4b8abdd4dfc4
DOI: 10.1101/2020.12.02.406835

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