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Article

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

2024-11-02

Abstract excerpt

<h4>ABSTRACT</h4> Of all the gynecologic malignancies, Ovarian cancer (OC) has the highest mortality rate, partly attributable to its propensity for chemotherapy resistance. The most common sub-type of OC is serous, of which High-Grade Serous Ovarian Cancer (HGSOC) is the most lethal sub-type. Elevated expression of Protein Tyrosine Phosphatase 4 A3 (PTP4A3) is implicated in tumour cell invasion and metastasis, b...

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Literature Corpus work
e26f2bf8-af0f-5a08-8050-3bed0f94612f
DOI
10.1101/2024.10.28.620719
Open publication

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Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugsDOI 10.1101/2024.10.28.620719
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