Article

PTOV1 Exerts Pro-oncogenic Role in Colorectal Cancer by Modulating SQSTM1-Mediated Autophagic Degradation of p53

2024-12-19

Abstract excerpt

<title>Abstract</title> <p>Background The incidence and mortality of colorectal cancer (CRC) are increasing rapidly worldwide. Prostate Tumor Overexpressed 1 (PTOV1) is overexpressed and associated with malignant phenotypes in various types of tumors. However, the detailed roles of PTOV1 and its underlying mechanism in CRC remain unclear. Methods The clinical significance of PTOV1 was assessed in clinical datab...

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Literature Corpus work: c63577c1-1f8d-56e8-92dc-f1502f44aebe
DOI: 10.21203/rs.3.rs-5421185/v1

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