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Article

Establishment of Novel High-Grade Serous Ovarian Carcinoma Cell Line OVAR79.

International journal of molecular sciences - 10 Dec 2024

Shnaider Polina V, Malyants Irina K, Ivanova Olga M, Gordeeva Veronika S, Svirina Ekaterina A, Zakharzhevskaya Natalya B, Shagaleeva Olga Y, Selezneva Oksana V, Bogomazova Alexandra N, Lukina Maria M, Aleshikova Olga I, Babaeva Nataliya A, Slonov Andrey V, Shender Victoria O

Abstract excerpt

High-grade serous ovarian carcinoma (HGSOC) remains the most common and deadly form of ovarian cancer. However, available cell lines usually fail to appropriately represent its complex molecular and histological features. To overcome this drawback, we established OVAR79, a new cell line derived from the ascitic fluid of a patient with a diagnosis of HGSOC, which adds a unique set of properties to the study of...

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Cell Movement
Cell Proliferation
Class I Phosphatidylinositol 3-Kinases
Cystadenocarcinoma, Serous

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Grading

Ovarian Neoplasms

PTEN Phosphohydrolase

Tumor Suppressor Protein p53

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PMID: 39769003
DOI: 10.3390/ijms252413236

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