Article
The up-regulation of PAK2 indicates unfavorable prognosis in patients with serous epithelial ovarian cancer and contributes to paclitaxel resistance in ovarian cancer cells.
2023-10-16
Abstract excerpt
<title>Abstract</title> <p>The main challenge in the treatment of ovarian cancer has been the development of resistance to chemotherapy. Previous studies have reported over-expression of PAK2 in various cancers through different mechanisms. The objective of this study was to investigate whether up-regulation of PAK2 contributes to chemo-resistance and poor prognosis in ovarian cancer. Bioinformatics analysis was...
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Identifiers and source
- Literature Corpus work
- fdb9f56e-13d1-528b-ab9f-6dd164876b25
- DOI
- 10.21203/rs.3.rs-3420261/v1