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Article

Establishment and characterization of a platinum- and paclitaxel-resistant high grade serous ovarian carcinoma cell line.

Human cell - 1 Jul 2017

Teng Pang-Ning, Bateman Nicholas W, Wang Guisong, Litzi Tracy, Blanton Brian E, Hood Brian L, Conrads Kelly A, Ao Wei, Oliver Kate E, Darcy Kathleen M, McGuire William P, Paz Keren, Sidransky David, Hamilton Chad A, Maxwell G Larry, Conrads Thomas P

Abstract excerpt

High grade serous ovarian cancer (HGSOC) patients have a high recurrence rate after surgery and adjuvant chemotherapy due to inherent or acquired drug resistance. Cell lines derived from HGSOC tumors that are resistant to chemotherapeutic agents represent useful pre-clinical models for drug discovery. Here, we describe establishment of a human ovarian carcinoma cell line, which we term WHIRC01, from a...

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PMID: 28251557
DOI: 10.1007/s13577-017-0162-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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