Article

High-resolution reconstruction of cell-type specific transcriptional regulatory processes from bulk sequencing samples

2025-04-08

Abstract excerpt

Biological systems exhibit remarkable heterogeneity, characterized by intricate interplay among diverse cell types. Resolving the regulatory processes of specific cell types is crucial for delineating developmental mechanisms and disease etiologies. While single-cell sequencing methods such as scRNA-seq and scATAC-seq have revolutionized our understanding of individual cellular functions, adapting bulk genome-wide...

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Literature Corpus work: f7bd87a3-293d-55c9-9bf2-c32508a65795
DOI: 10.1101/2025.04.02.646189

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