Article

Genomic Architecture of Cells in Tissues (GeACT): Study of Human Mid-gestation Fetus

2020-04-13

Abstract excerpt

<h4>Summary</h4> By circumventing cellular heterogeneity, single cell omics have now been widely utilized for cell typing in human tissues, culminating with the undertaking of human cell atlas aimed at characterizing all human cell types. However, more important are the probing of gene regulatory networks, underlying chromatin architecture and critical transcription factors for each cell type. Here we report the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 41e1062a-da37-575e-932d-b6b2f9ff5db3
DOI: 10.1101/2020.04.12.038000

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genomic Architecture of Cells in Tissues (GeACT): Study of Human Mid-gestation FetusDOI 10.1101/2020.04.12.038000Read

A human cell atlas of fetal gene expressionSemantic proximity Read

Comprehensive identification of fetal cis-regulatory elements in the human genome by single-cell multi-omics analysisSemantic proximity Read

A limited set of transcriptional programs define major cell typesSemantic proximity Read

A Multiomics, Spatiotemporal, and Single Cell Atlas for Mapping Cell-Type-Specific Dysregulation at the Maternal-Fetal InterfaceSemantic proximity Read

A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fatesSemantic proximity Read

Chromatin and gene-regulatory dynamics of human pulmogenesis by single cell multiomic sequencingSemantic proximity Read

Deconvolution of single-cell multi-omics layers reveals regulatory heterogeneitySemantic proximity Read

Single-cell transcriptome profiling of an adult human cell atlas of 15 major organsSemantic proximity Read

An atlas of TF driven gene programs across human cellsSemantic proximity Read

Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal–fetal interfaceSemantic proximity Read

Single-cell transcriptional profiling reveals cellular and molecular divergence in human maternal-fetal interfaceSemantic proximity Read

An integrated single cell and spatial omics atlas of human prenatal developmentSemantic proximity Read