Article

Structural basis for differential targeting properties of small RNAs in plants and animals

2022-07-21

Abstract excerpt

microRNAs (miRNAs) regulate gene expression in plants and animals. Animals use miRNAs to sculpt the transcriptome, with each miRNA modestly repressing hundreds of otherwise unrelated targets. By contrast, each plant miRNA potently silences a small number of physiologically related targets. Here, we show that this major functional distinction depends on a minor structural difference between plant and animal Argonau...

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Literature Corpus work: e24fb303-2f45-54bb-993e-e998f0fe3f83
DOI: 10.1101/2022.07.20.500788

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