Article

Programmed Manipulation of RNA Targets By Human Argonaute 2

2026-02-02

Abstract excerpt

Nucleic acid manipulation using programmable ribonucleoprotein complexes (RNPs) has enabled transformative research tools and led to new therapeutic strategies. RNA directly regulates diverse cellular processes, 1 is a crucial mediator of protein synthesis, and offers advantages in therapeutic targeting and fundamental discovery complementary to those of DNA. 2 ISC- 3 and Cas-based 4,5 scaffolds where the RNP...

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Literature Corpus work: 0484ebc3-c213-520d-9cd2-4f3085fbde31
DOI: 10.64898/2026.02.01.703109

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