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Article

Phosphorylation of human Argonaute proteins affects small RNA binding.

Nucleic acids research - 1 Mar 2011

Rüdel Sabine, Wang Yanli, Lenobel René, Körner Roman, Hsiao He-Hsuan, Urlaub Henning, Patel Dinshaw, Meister Gunter

Abstract excerpt

Argonaute (Ago) proteins are highly conserved between species and constitute a direct-binding platform for small RNAs including short-interfering RNAs (siRNAs), microRNAs (miRNAs) and Piwi interacting RNAs (piRNAs). Small RNAs function as guides whereas Ago proteins are the actual mediators of gene silencing. Although the major steps in RNA-guided gene silencing have been elucidated, not much is known about...

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Identifiers

PMID: 21071408
DOI: 10.1093/nar/gkq1032
PMCID: PMC3064767

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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