Article
Functional analysis of three Arabidopsis ARGONAUTES using slicer-defective mutants.
The Plant cell - 1 Sept 2012
Carbonell Alberto, Fahlgren Noah, Garcia-Ruiz Hernan, Gilbert Kerrigan B, Montgomery Taiowa A, Nguyen Tammy, Cuperus Josh T, Carrington James C
Abstract excerpt
In RNA-directed silencing pathways, ternary complexes result from small RNA-guided ARGONAUTE (AGO) associating with target transcripts. Target transcripts are often silenced through direct cleavage (slicing), destabilization through slicer-independent turnover mechanisms, and translational repression. Here, wild-type and active-site defective forms of several Arabidopsis thaliana AGO proteins involved in...
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