Article

Beyond microRNAs: Analysis of chimeric reads characterises the diverse targetome of AGO2-mediated regulation

2023-09-25

Abstract excerpt

Argonaute proteins are instrumental in regulating RNA stability and translation. AGO2, the major mammalian Argonaute protein, is known to primarily associate with microRNAs, a family of small RNA ‘driver’ sequences, and identifies its targets primarily via a ‘seed’ mediated partial complementarity process Despite numerous studies, a definitive experimental dataset of AGO2 'driver'-'target' interactions remains elu...

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Literature Corpus work: 2c61188c-4a6d-5e8b-9cbc-c21c2f7e7ce5
DOI: 10.21203/rs.3.rs-3361772/v1

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