Article

Distinct memory CD4 subset tropism of two CCR5-tropic HIV-1 in a rapid progressor

2025-01-23

Abstract excerpt

CCR5 tropic HIV-1 mainly infect memory CD4 + T cells. Memory CD4 + T cells are heterogenous which comprise central memory (CM), transitional memory (TM) and effector memory (EM) subsets based on cell differentiation stages. Previous studies demonstrate that low viral burden in the CM subset correlates with long-term non-progressive HIV-1 infection (1, 2) and is a hallmark of non-pathogenetic SIV infection (3, 4)...

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Literature Corpus work: e2294b6d-80ef-5ca4-81bb-9c5b40b95a7e
DOI: 10.1101/2025.01.21.634053

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