Article

HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infections

2022-05-10

Abstract excerpt

Upon infection, HIV disseminates throughout the human body within 1-2 weeks. However, its early cellular targets remain poorly characterized. We analyzed productively and latently infected cells in blood and lymphoid tissue from individuals in acute infection. The phenotype of productively infected cells rapidly evolved with time and differed between blood and lymph nodes. The TCR repertoire of productively infect...

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Identifiers and source

Literature Corpus work: 37c38e93-f667-526c-8988-dd746edfc230
DOI: 10.1101/2022.05.10.491275

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