Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

T-cell heterogeneity, progenitor-progeny relationships, and function during latent and chronic viral infections.

Immunological reviews - 1 Jul 2023

Sandu Ioana, Oxenius Annette

Abstract excerpt

Upon resolution of an acute viral infection, during latent-reactivating infection and during chronic active infections virus-specific T-cells differentiate into distinct subsets that differ in phenotype, longevity, transcriptional, metabolic, and epigenetic profiles, and effector functions. With recent advances in single-cell profiling, this substantial heterogeneity has become apparent and new subsets of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD8-Positive T-Lymphocytes
Share to Cell Differentiation
Share to Immunologic Memory

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Virus Diseases

Source

Identifiers

PMID: 37038909
DOI: 10.1111/imr.13203

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

T-cell heterogeneity, progenitor-progeny relationships, and function during latent and chronic viral infections.PMID 37038909Read ↗

Progenitor and Terminal Subsets of CD8 <sup>+</sup> T Cells Cooperate to Contain Chronic Viral InfectionSemantic proximity Read ↗

Human virus‐specific CD8<sup>+</sup> T cells: diversity specialistsSemantic proximity Read ↗

Clonally expanded virus-specific CD8 T cells acquire diverse transcriptional phenotypes during acute, chronic, and latent infectionsSemantic proximity Read ↗

Clonally distinct differentiation trajectories shape CD8 <sup>+</sup> memory T cell heterogeneity after acute viral infections in humansSemantic proximity Read ↗

HIV rapidly targets a diverse pool of CD4+ T cells to establish productive and latent infectionsSemantic proximity Read ↗

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell populationSemantic proximity Read ↗

Within host RNA virus persistence: mechanisms and consequencesSemantic proximity Read ↗

Clonally Expanded Virus-Specific CD8 T Cells Acquire Diverse Transcriptional Phenotypes During Acute, Chronic, and Latent Infections.Semantic proximity Read ↗

CMV-specific clonal expansion in human Th1 and GZMK⁺ CD8⁺ T cellsSemantic proximity Read ↗

Striking a Balance—Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic StimulationSemantic proximity Read ↗

Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalitiesSemantic proximity Read ↗

HIV-1 Latency and Viral Reservoirs: Existing Reversal Approaches and Potential Technologies, Targets, and Pathways Involved in HIV Latency StudiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.