Article
Longitudinal analysis of subtype C envelope tropism for memory CD4+ T cell subsets over the first 3 years of untreated HIV-1 infection.
Retrovirology - 6 Aug 2020
Gartner Matthew J, Gorry Paul R, Tumpach Carolin, Zhou Jingling, Dantanarayana Ashanti, Chang J Judy, Angelovich Thomas A, Ellenberg Paula, Laumaea Annemarie E, Nonyane Molati, Moore Penny L, Lewin Sharon R, Churchill Melissa J, Flynn Jacqueline K, Roche Michael
Abstract excerpt
BACKGROUND: HIV-1 infects a wide range of CD4+ T cells with different phenotypic properties and differing expression levels of entry coreceptors. We sought to determine the viral tropism of subtype C (C-HIV) Envelope (Env) clones for different CD4+ T cell subsets and whether tropism changes during acute to chronic disease progression. HIV-1 envs were amplified from the plasma of five C-HIV infected women from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.